About megatomi.com
About megatomi.com
Blog Article
Our new Clear+ tissue clearing strategy is the only technique that delipidates samples without any adjust in morphology and with minimal effect on structural integrity.
Megatome is really a vibrating microtome built to area a broad choice of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome permits higher-throughput tissue sectioning with uniform area profile, along with negligible tissue injury and knowledge loss.
Antibodies may well consider months to diffuse via just a few millimeters of tissue, using a steep labeling gradient from surface area to core.
Megatome is suitable for accuracy: the blade vibrates at a better frequency and bigger amplitude variety than other microtomes, and incorporates a unique deflection Handle system.
SE takes advantage of a rotational electric powered area to disperse hugely electromobile molecules (for instance antibodies or surfactant micelles) all over a porous sample without the need of damaging electrically charged constructions in the tissue. This allows 2-four day clearing of intact organs,
Our preformulated EasyIndex Remedy raises and homogenize the refractive index of delipidated tissue samples, rendering them absolutely transparent. This permits light penetration in the sample and ensures the acquisition of high-resolution, in-focus megatomi.com image data.
Megatome is actually a novel microtome that allows for high-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with small tissue hurt and data reduction.
It’s time for you to update your microtome to Megatome. With correct higher-frequency slicing for an unmatched selection of sample sizes and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for numerous purposes.
The SmartSPIM light-weight sheet microscope delivers unparalleled resolution and acquisition pace through intact tissue volumes, even though its modular design and style enables you to upgrade and customise unique factors.
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Protect avoids the variability of hydrogel embedding and the knowledge loss from PFA preservation, shielding specimens for several rounds of processing.
Leverage the Clear+ tissue clearing system, coupled with eFLASH and patented stochastic electrotransport technologies, to fast very clear and label whole organs. Essential highlights and attributes involve:
Our novel Defend tissue preservation system types intramolecular bonds applying polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.